Cytokeratin positive T cell malignant lymphoma

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Cytokeratin positive T cell malignant lymphoma

A high grade T cell malignant lymphoma is described in which weak staining of tumour cells for leucocyte common antigen and T cell markers coexisted with strong positive cytoplasmic staining with the anticytokeratin marker CAM 5.2. This is the first report of non-CD30 positive T cell lymphoma showing cytokeratin positivity. On ultrastructural examination there was no evidence of epithelial diVe...

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Cytokeratin positive T cell malignant lymphoma.

A high grade T cell malignant lymphoma is described in which weak staining of tumour cells for leucocyte common antigen and T cell markers coexisted with strong positive cytoplasmic staining with the anticytokeratin marker CAM 5.2. This is the first report of non-CD30 positive T cell lymphoma showing cytokeratin positivity. On ultrastructural examination there was no evidence of epithelial diff...

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Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory

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Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells.

Studies in an in vitro model of cutaneous T-cell lymphoma (CTCL) demonstrated that CTCL cell proliferation is stimulated by direct contact with autologous, immature dendritic cells (DCs), suggesting that CD4(+) CTCL cell division is driven by antigens presented by DC major histocompatibility complex (MHC) class 2. We now report that the T-cell receptor (TCR) of the CD4(+) CTCL cells is triggere...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1998

ISSN: 0021-9746

DOI: 10.1136/jcp.51.5.404